By W Hoyle, Mike Lancaster
Generating huge amounts of waste is not just environmentally unacceptable, it's also now not practicable in fiscal phrases. The chemical undefined, really the speciality and prescription drugs sectors, is changing into more and more conscious of the benefits linked to fresh expertise, fairly by way of aggressive virtue and environmental advantages. Bringing jointly an realizing of the recommendations and values of unpolluted know-how through the use of case reports from a few top ecu international locations, this ebook offers an perception into topics resembling catalysis; procedure intensification; and the way to degree the "green" price of a technique. It additionally highlights the function performed via either the chemical and chemical engineering disciplines within the improvement of cleanser methods. fresh expertise for the Manufacture of Speciality chemical substances will turn out invaluable interpreting for method improvement chemists and engineers, fairly these within the specialities and prescription drugs sectors, and also will be a massive resource of training fabric for the starting to be variety of fresh expertise chemistry classes.
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Additional info for Clean Technology for the Manufacture of Specialty Chemicals
2000,55,2401. 19. D. Trent, D. Tirtowidjojo and G. Quardener, BHR Group Con$ Ser. , 1999, 38 (Process Intensification for the Chemical Industry), 2 17. SULPHONES BY OXIDATION - THE DEVELOPMENT PERSPECTIVE David A Jackson*, Howard Rawlinson & Oskar Barba Zeneca Process Technology Department Huddersfield Works, Leeds Road Huddersfield Yorkshire HD2 1FF 1 INTRODUCTION The purpose of this paper is to present a perspective of the “Green Chemistry” Issues typically pertinent to the manufacture of Fine Chemicals.
Bearing in mind the dramatic size reduction which is sought, process intensification will probably involve novel and unusual approaches to equipment design. It is not a strategy for the faint-hearted. Herein lies one of its main disadvantages, namely the lack of new design codes to engender confidence in those who specify new equipment. Radical and unconventional approaches will be the order of the day. Many searching questions will be posed, such as the need for turbulent flow in pipes, the use of batch rather than continuous operation and the application of merely terrestrial acceleration to multi-phase systems, to name but a few.
Following extensive discussions with potential industrial partners in the pharmaceuticals/fine chemicals area, it has become evident that there is considerable interest in the opportunities presented by spinning disc reactor (SDR) technology. A reactor design based on spinning discs provides an excellent heat and mass transfer environment for the reacting liquid and promises to overcome these disadvantages. SDR technology offers the possibility of a step change in manufacturing operations, particularly with respect to the following attributes:1) Ability to cope with very fast exothermic reactions (corresponding to heat fluxes of upto 1 0 0 kW/m2.