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Additional resources for Cyclophosphamide - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References
The specific aims of our first modest (25,000 dollars) grant was to build the infrastructure for SWOG participation-- hire and train CRAs and research nurses, provide travel for physician investigators to become involved in SWOG, and recruit affiliated community cancer centers. This has largely been accomplished. Objectives for the new Southwest Oncology Group Institutional Grant are the following: 1. To develop and pilot promising strategies for cancer at Columbia for eventual evaluation in larger clinical trials in the Southwest Oncology Croup.
Tumor cells from rodents will be examined for scavenger enzyme, mismatched repair enzymes. ; Senior Staff Investigator; Internal Medicine; Case Western Reserve Univ-Henry Ford Hsc Research Administraion Cfp-046 Detroit, Mi 48202 Timing: Fiscal Year 2002; Project Start 01-JUN-2001; Project End 31-MAY-2005 Summary: (Applicant's Abstract) Our long-term goal is to develop novel biotherapies that will specifically target and destroy residual leukemia. The proposed studies will test the general hypothesis that site-directed gene therapy with hematopoietic progenitor cells, genetically modified to secrete human tumor necrosis factor-alpha (hTNF-a), will significantly increase the destruction of leukemia cells remaining after high-dose chemotherapy/bone marrow (BM) transplantation.
David Krag is an active member of the Breast Core Committee and is helping CALBG develop a protocol for sentinel node staging for women with early stage breast cancer. Dr. Seth Harlow will assume Dr. Krag's role as member of the Surgery Committee. Dr. Donald Weaver participates extensively in pathology group activities and has a major interest in breast cancer. Drs. Michael Cooper, Barbara Grant, and Richard Branda have major interest in urologic cancer, leukemia and lymphoma, and nutrition and cancer, respectively, and have developed concepts for CALGB clinical investigations.