Die Haschischstudie by Drogen, Tony Buehrer PDF

By Drogen, Tony Buehrer

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9) Besides these granule-containing Langerhans cells there are so-called indeterminate cells in the epidermis. For a long time they were thought to be a different dendritic cell type (for review see WOLFF 1972). Probably these cells are related to Langerhans cells and to interdigitating cells of the lymphatic tissue. Except for the Birbeck granule, these cells are isomorphous and form part of a universal system including thymus, spleen, lymph node, tonsil and stratified epithelia. It may well be that indeterminate cells of the epidermis and interdigitating cells of lymphoid organs turn out to be identical cell types.

MTP Press, Lancaster, pp 43-61 Chopra DP, Flaxman BA (1972) Human epidermal cell cycle in vitro. Br J DermatoI87:1317 Christophers E (1970) Eine neue Methode zur Darstellung des stratum corneum. Arch Klin Exp Derm 237:717-721 Christophers E (1971 a) Die epiderm ale Columniirstruktur. Z Zellforsch 114:441-450 Christophers E (1971 b) Cellular architecture of the stratum corneum. J Invest Dermatol 56:165-169 Christophers E (1972a) Correlation between columns formation, thickness and rate of new cell production in guinea pig epidermis.

With data given for Ts (or even TM or Td the turnover or a tissue compartment of the entire organ may be calculated provided the number of cells present in this compartment is known. Therefore rigorous quantification of epidermal cellularity applying Abercombie's correction for tissue geometry is needed (LAURENCE and CHRISTOPHERS 1976). 6 basal cells in mitosis per thousand cells. The mitotic process lasts around 90 min. Between 3% and 5% of cells are in DNA synthesis and the length of the S phase tends to be around 7 h.

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