By Christopher Salgado, Stan Monstrey, Miroslav Djordjevic
Some humans pursue clinical interventions as a part of the method of expressing their gender, and a growing number of gender confirmation surgical procedures are being played. This booklet, which gives complete insurance of the topic, is edited through 3 well-respected and skilled authors with over 20 participants from all over the world. It gains complete assurance of either clinical and surgery, supported through over 350 full-color drawings and pictures and surgical video.
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Extra info for Gender Affirmation: Medical and Surgical Perspectives
There is no consensus regarding when and how often repeat biopsy should be performed following a HGPIN diagnosis. Most studies recommend repeat biopsy at 3 to 6 months or 6 to 12 months, or even at 36 months. Without a clear guideline, such recommendations should be individualized and based on clinical parameters and the patient’s and physician’s preference. Since the prostate lobe contralateral to the site in which the initial HGPIN was diagnosed also carries considerable risk for cancer, albeit not as high as the side in which HGPIN was diagnosed, the rebiopsy should sample the entire gland with an emphasis on the area in which HGPIN was initially found.
The clinical significance of NE diﬀerentiation in these tumors is uncertain and most of the studies have shown no eﬀect on outcomes. , prominent eosinophilic cytoplasmic granules on light microcopy and neurosecretory granules on electron microscopy). The clinical significance of PCa with Paneth-cell– like diﬀerentiation is not completely understood, although studies have shown that seemingly poorly diﬀerentiated PCa with Paneth-cell–like diﬀerentiation has a favorable prognosis. Prostate carcinoid tumor is a well-diﬀerentiated NE tumor with the classical morphology of carcinoid tumor arising in the prostatic parenchyma.
J Urol 1988; 139(1):61–65  Epstein JI, Allsbrook WC Jr Amin MB, Egevad LL ISUP Grading Committee. The 2005 International Society of Urological Pathology (ISUP) Consensus Conference on Gleason Grading of Prostatic Carcinoma. Am J Surg Pathol 2005; 29 (9):1228–1242  van der Kwast TH, Amin MB, Billis A et al. ISUP Prostate Cancer Group. International Society of Urological Pathology (ISUP) Consensus Conference on Handling and Staging of Radical Prostatectomy Specimens. Working group 2: T2 substaging and prostate cancer volume.