Genetics and Evolution of Aging by Michael R. Rose, Caleb E. Finch PDF

By Michael R. Rose, Caleb E. Finch

Aging is a kind of topics that many biologists believe is essentially unknown. hence, they typically think cozy supplying super facile generalizations which are both unsupported or at once refuted within the experimental literature. regardless of this unlucky precedent, getting older is a truly vast phenomenon that calls out for integration past the mere accumulating jointly of effects from disparate laboratory organisms. With this in brain, half One deals numerous varied artificial views. The editors, Rose and Finch, supply a verbal synthesis of the sphere that intentionally makes an attempt to examine getting older from each side, the evolutionary and the molecular. The articles by way of Charlesworth and Clark either supply inhabitants­ genetic views on getting older, the previous extra mathematical, the latter extra experimental. Bell takes a very assorted method, arguing that getting older is probably not the results of evolutionary forces. Bell's version in its place proposes that getting older might come up from the revolutionary deterioration of power host­ pathogen interactions. this can be the 1st specific e-book of this version. It marks whatever of a go back to the kind of getting older theories that predominated within the 1950's and 1960's, theories just like the somatic mutation and mistake disaster theories. we are hoping that the reader could be interested in the distinction in perspectives among the articles in keeping with evolutionary idea and that of Bell. MR. Rose and C. E. Finch (eds. ), Genetics and Evolution of getting older, 5-12, 1994. © 1994 Kluwer educational Publishers. The J aniform genetics of getting older 2 Michael R. Rosel & Caleb E.

Show description

Read or Download Genetics and Evolution of Aging PDF

Best gerontology books

Senior Centers: Opportunities For Successful Aging - download pdf or read online

The publication good points real-life vignettes that carry the textual content to existence, supplying readers with the chance to work out how older adults take advantage of senior facilities. The Appendix incorporates a worthy checklist of assets to boot. pros who paintings with older adults together with social employees, sport therapists, nurses, gerontologists, directors, and scholars will locate this ebook to be a important source.

Download e-book for kindle: The Social Context of Ageing: A Textbook of Gerontology by Christina Victor

This accomplished textual content makes a speciality of the social contexts of aging, taking a look at the range of growing old and older humans, and at various factors which are vital to studies of outdated age and ageing. It comprises key chapters on: theoretical and methodological bases for the examine of getting older demographic context of the 'ageing' inhabitants wellbeing and fitness and ailment relatives and social networks formal and casual care and different prone for older humans.

The Economics of an Aging Society - download pdf or read online

Written through major thinkers within the box, this article presents an in-depth research of the industrial and coverage matters linked to person and inhabitants getting older. The textual content has a powerful coverage concentration in line with demographic and monetary research, making this ebook either available and tough to readers with restricted mathematical history.

Download e-book for iPad: Handbook of Aging and the Social Sciences, Seventh Edition by Linda George

The guide of getting older and the Social Sciences, 7e, summarizes the learn literature at the social points of getting older. The 7e could have 88% new fabric and authors with 25 chapters: 22 of the chapters may be on thoroughly new themes. Separated into 4 sections, the totally revised guide will conceal idea and techniques, getting older and social constitution, social components and social associations, and getting older and society.

Additional resources for Genetics and Evolution of Aging

Sample text

Selection occurs in HIV populations during serial passage in cell culture. , 1991). , 1992). , 1991), and may occur even in highly conserved regions of the viral genome. Hoxie et al. (1991) found that the passage of attenuated HIV-l with low binding affinity for CDA cells eventually resulted in the appearance of cytopathic variants whose binding affinities were comparable with those of normal cytopathic HIV-2 isolates. , 1991). L'Age-Stehr et al. (1990) observed the evolution of a shorter latent period and increased virulence towards T-cells when HIV was maintained in cell culture.

1991). , 1990). Within-host selection in relation to other theories The material that I have reviewed above shows that all the preconditions required by the hypothesis of within-host selection are met, at least in some instances. Whether or not they are generally true must await the accumulation of evidence. However, the availability of methods for amplifying viral genomes present at very low abundance in host tissues will make it possible to decide very soon whether the single most important and most surprising observation which the theory requires, the universality of persistent viral infection, is really the case.

Partridge, L. H. Barton, 1993. Optimality, mutation, and the evolution of ageing. Nature 362: 305-311. , P. Pignatelli & L. Partridge, 1993. Evolutionary effects of selection on age at reproduction in larval and adult Drosophila melanogaster. Evolution 47: 445-455. , 1984. Laboratory evolution of postponed senescence in Drosophila melanogaster. Evolution 38: 1004--1010. R. & B. Charlesworth, 1981. Genetics of life history of Drosophila melanogaster. II. Exploratory selection experiments. Genetics 97: 187-196.

Download PDF sample

Rated 4.06 of 5 – based on 3 votes

About the Author

admin