Download e-book for iPad: Investigative Urology 3 by B. J. Schmitz-Dräger, D. Rohde, H. Frenzel, R. Ackermann

By B. J. Schmitz-Dräger, D. Rohde, H. Frenzel, R. Ackermann (auth.), Professor Dr. Herbert Rübben, Professor Dr. Dieter Jocham, Professor Dr. Günther H. Jacobi (eds.)

The first symposium of the operating staff on experimental urology of the German Society of Urology used to be held in Cologne in 1972. It used to be intended to be a platform to give and, particularly, to debate experimental experiences constructing new diagnostic and healing techniques, and to advertise in­ novation in urology in Germany. This plan was once good got, and through the final sixteen years either the variety of individuals from different ecu and in a foreign country international locations and the quantity and caliber of displays were always expanding. on the most up-to-date assembly, held in Aachen in 1988, new information have been offered on renal mobilephone melanoma, andrology, prostatic melanoma and adenoma, bladder melanoma, urinary diversion, urodynamics, renal pathophysiology, transplantation and the pathogenesis and therapy of urolithiasis. the current ebook includes forty four of the 109 papers given on the Aachen assembly, overlaying either simple and scientific study. it will likely be of eminent curiosity to all scientifically minded urologists, oncologists, neurophysiolo­ gists, endocrinologists, and pathologists since it is a synopsis of all of the significant clinical study at the moment being carried out in urology in Europe. There are not any different books on hand which supply as complete a canopy­ age of modern experimental matters in urology. the purpose of the sequence Inves­ tigative Urology is to illustrate the continual improvement of study in urology and to motivate all colleagues attracted to experimental urol­ ogy to proceed their vital actions and create new overseas co­ operation.

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0--0, Growth control; - , cytotoxic control; e______e, lOng/dish; 0--0, lOOng/dish; 0-0, 1000ng/dish. B IFN-y. lOE7 IV/mg. 0--0, Growth control; - , cytotoxic control; e______e, 160ng/dish; 0--0, 1600ng/dish; 0-0, 16000 ng/dish. C TNF. lOE7 IV/mg. 0--0, Growth control; - , cytotoxic control; e______e, lOng/dish; 0--0, lOOng/dish; 0-0, 1000ng/dish est concentration of 16000ng/dish still gives rise to about 85% of colonies as compared with the growth control. Synergistic Antiproliferative Effects on Colony Formation of NU-12, HAM-II, and HAM-III Renal Tumor Cells After Application of a Single Dose of Combinations of IFN-a, IFN-y, and/or TNF Because IFNs and TNF can act synergistically (Hubbell et al.

20 M. Harasim et al. 1 0 b 10 Time after inoculation Fig. 23, b. lb). Figure 2 contains a selection of the numerous growth curves of the human renal cell carcinomas in nude mice presently studied. Figure 2a depicts growth curves of various human renal cell carcinomas. They show that tumor growth in the nude mouse differs considerably between the different tumors. It ranges from Gompertzian growth with an early delay (NT-41) or initial exponential growth with late and considerable delay (NT-42) to complete exponential growth with different slopes (NT-9, NT-28).

Have shown no evidence of a tumor under histological examination were taken as controls. All specimens were snap frozen immediately after the nephrectomy, wrapped in metal foil to prevent dehydration, and stored in liquid nitrogen. The delay before freezing was no more than 30 min. The EGF-receptors were identified by an indirect immunoperoxidase technique using a murine monoclonal antibody. This IgG1 antibody was raised against the extracellular domain of the EGF-receptor of A-431 cells (Schreiber et al.

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