Download e-book for iPad: Oral Pharmacotherapy for Male Sexual Dysfunction: A Guide to by Gregory A. Broderick

By Gregory A. Broderick

For the iteration that reached sexual adulthood within the Nineteen Sixties, the “pill” turned synonymous with sexual freedom and commenced a sexual revolution. for girls it intended freedom from the phobia of being pregnant, and for males superior sexual chance. the recent period of the capsule has not anything to do with fertility, yet every thing to do with intercourse. the 1st orally potent prescr- tion drug for treating erectile disorder (ED) was once advertised in 1998. ® Sildenafil (Viagra ) has rejuvenated the getting older male veterans of the sexual revolution, eternally replaced the technological know-how of sexual medication, and tra- shaped society’s standpoint on getting older and intercourse. This classification of substances, referred to as oral phosphodiesterase inhibitors (PDE-type 5), is extremely powerful within the remedy of ED. for the reason that its advent there was a far better awa- ness of ED, its comorbidities, and its results at the caliber of existence. In 1997, whereas getting ready to handle the Endocrine Society at the get together of the 92nd American Urological organization assembly, I first checked out the p- scientific reviews of sildenafil. i assumed “this will switch every thing” and it truly has―changing perform styles in sexual medication, and the at- tudes of sufferers, capability sufferers, and their companions. new PDE-type ® ® five inhibitors, tadalafil (Cialis ) and vardenafil (Levitra ), have been first licensed through the eu Committee for Proprietary Medicinal items and to that end by way of the meals and Drug management in 2003 and 2004.

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J Sex Marital Ther 23(3):195–207. 4. Wessells H, Lue TF, McAninch JW. (1996) Penile length in the flaccid and erect states: guidelines for penile augmentation. J Urol 156:995–997. 5. Goldstein I, Udelson D. (1998) Axial penile rigidity: determinants and relation to hemodynamic parameters. Int J Impot Res 10(Suppl 2):S28–S33; discussion S49– S51. 6. Nehra A, Azadzoi KM, Moreland RB, et al. (1998) Cavernosal expandability is an erectile tissue mechanical property which predicts trabecular histology in an animal model of vasculogenic erectile dysfunction.

20 Carrion et al. 8. Hsu GL, Brock BG, Martinez-Pineiro L, et al. (1992) The three dimensional structure of the human tunica albuginea: anatomical and ultrastructural levels. Int J Impot Res 4:117–129. 9. Hinman FJ. (1998) Correction of penile defects. , Atlas of Urologic Surgery, 2nd Ed. Philadelphia, PA: WB Saunders Co, pp. 165–166. 10. Brock G, Hsu GL, Nunes L, et al. (1997) The anatomy of the tunica albuginea in the normal penis and Peyronie’s disease. J Urol 157:276–281. 11. Goldstein AM, Padma-Nathan H.

Cases of secondary arteriogenic ED can be treated by penile revascularization (91). Posterior urethroplasty for stricture is thought to be associated with a small but significant risk of ED. The data for anterior strictures are much better, with a recent large series reporting only one new onset of ED among 168 consecutive patients who underwent anterior urethroplasty (92). Surgical trauma is also commonly associated with ED. Radical prostatectomy is probably the most commonly performed urological procedure associated with ED.

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