By Ch. H. Bangma, D.W.W. Newling
This is often the 7th monograph within the sequence growth and Controversies in Oncologic Urology (PACIOU). Containing contributions from specialists from all over the world, this ebook offers the main updated info on hand at the mechanisms and therapy of prostate melanoma and male sexual disorder. Highlighting the connection among study effects and the scientific perform, the discussions contain the prognosis and remedy of benign prostate melanoma, prognosis and results in in the neighborhood restrained prostate melanoma, epidemiology, threat elements, renal melanoma, and the result of section I and section II trials of latest medicines.
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Additional resources for Prostate and Renal Cancer, Benign Prostatic Hyperplasia, Erectile Dysfunction and Basic Research: An Update (Progress & Controversies in Oncological Urology)
RP patients were healthier and younger than EBRT patients, and this was reflected by better generic SF-36 scores preceding treatment. Madalinska concluded that the EBRT group’s scores were similar and the RP group’s scores better than age- and sex-adjusted reference scores from the Dutch general population. The studies from Galbraith, Madalinska, Talcott (SF-36), Lee (FACT scales) and Potosky (five SF-36 scales) reported analyses of differences in generic QoL after treatment between the RP and EBRT groups, with adjustment for baseline characteristics (age in all studies; baseline QoL in Madalinska and Lee; tumor characteristics and/or various demographic characteristics in Lee, Talcott and PCOS).
There is no convincing evidence available to show that either treatment is more effective in saving quantity of life than the other. A recent report of a trial comparing RP and expectant management showed a significant reduction of prostate cancer mortality after RP, but a trial comparing RP and EBRT is not yet available1. Quality of life (QoL) issues become decisive in this situation. Among the first QoL studies of primary treatment for localized prostate cancer, that of Litwin and colleagues found no differences in general QoL between groups of men who had previously been treated by RP or EBRT, but the groups differed from men without prostate cancer regarding sexual, urinary and bowel function2.
Effects of endocrine treatment 31 In men for whom their sexuality is important, a decrease in sexual interest and/or erectile capability can result in psychological distress, difficulties with relationships and loss of self-esteem5. Indeed, Helgason’s group4 found that the decline in sexual function (including sexual desire, erectile capacity and orgasm pleasure) was the most common cause of disease-related stress in men with prostate cancer. While erectile dysfunction can be effectively treated20,21, there are no recognized effective therapies for loss of sexual interest21.