New PDF release: Prostate Cancer: Translational and Emerging Therapies

By Nancy A. Dawson, W. Kevin Kelly

Scientists have reached a serious element within the improvement of latest treatments for prostate melanoma. the data gleaned from the Human Genome venture, along the emergence of recent applied sciences for using genetic info has increased the physician's knowing of illness development and widened his armamentarium for prostate melanoma prevention and regulate. This expertly-written reference completely analyzes the clinical rules and methodologies at the back of the newest translational treatments and offers the required context, information, and reports for practitioners to choose applicable applicants for remedy and successfully follow new cures in scientific perform.

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Steadman DJ, Giuffrida D, Gelmann EP. 1. Nucl Acids Res 2000; 28:2389–2395. 174. Abdulkadir SA, Magee JA, Peters TJ, et al. 1 in adult mice induces prostatic intraepithelial neoplasia. Mol Cell Biol 2002; 22:1495–1503. 175. Ouyang X, DeWeese TL, Nelson WG, Abate-Shen C. 1 promotes increased oxidative damage in prostate carcinogenesis. Cancer Res 2005; 65:6773–6779. 176. Asatiani E, Huang WX, Wang A, et al. 1 suppressor gene in primary human prostate cancer. Cancer Res 2005; 65:1164–1173. 177. Voeller HJ, Augustus M, Madike V, Bova GS, Carter KC, Gelmann EP.

Cancer Res 2002; 62:338–340. 173. Steadman DJ, Giuffrida D, Gelmann EP. 1. Nucl Acids Res 2000; 28:2389–2395. 174. Abdulkadir SA, Magee JA, Peters TJ, et al. 1 in adult mice induces prostatic intraepithelial neoplasia. Mol Cell Biol 2002; 22:1495–1503. 175. Ouyang X, DeWeese TL, Nelson WG, Abate-Shen C. 1 promotes increased oxidative damage in prostate carcinogenesis. Cancer Res 2005; 65:6773–6779. 176. Asatiani E, Huang WX, Wang A, et al. 1 suppressor gene in primary human prostate cancer. Cancer Res 2005; 65:1164–1173.

The development of androgen-independent prostate cancer. Nat Rev Cancer 2001; 1:34–45. 22. Makridakis NM, di Salle E, Reichardt JK. Biochemical and pharmacogenetic dissection of human steroid 5 alpha-reductase type II. Pharmacogenetics 2000; 10:407–413. 23. Brinkmann AO, Blok LJ, de Ruiter PE, et al. Mechanisms of androgen receptor activation and function. J Steroid Biochem Mol Biol 1999; 69:307–313. 24. Roche PJ, Hoare SA, Parker MG. A consensus DNA-binding site for the androgen receptor. Mol Endocrinol 1992; 6:2229–2235.

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